Xylitol (sometimes labeled "birch sugar") is a sugar substitute found in sugar-free gum, mints, peanut butter, toothpaste, vitamins, and many "keto" and diabetic-friendly foods. To dogs it is extremely toxic: it triggers a massive insulin release that can cause fatal hypoglycemia within 30 minutes.

The problem is growing. The Pet Poison Helpline reports that xylitol-related cases were the 4th-most-common dog poisoning call in both 2024 and 2025, and remain nearly 75% higher in 2025 than they were in 2020. In 2024 the ASPCA Animal Poison Control Center logged more than 10,000 xylitol calls.

Even a little is lethal. As few as two pieces of certain sugar-free gum can sicken a small dog. Symptoms include vomiting, weakness, staggering, tremors, and seizures; liver failure can follow within 12–48 hours. Always read labels — some specialty peanut-butter brands still use xylitol.

The U.S. Congress revisited the issue with the proposed "Paws Off Act of 2025," which would require clear xylitol warnings on consumer products. Until labeling laws catch up, prevention is the only defense: store gum, candy, and medications out of reach, and never give your dog human food or toothpaste without checking the ingredients.

If you suspect ingestion, call your veterinarian or the ASPCA Animal Poison Control Center (888-426-4435) immediately. Minutes matter — do not wait for symptoms to appear.